I like the answers you received and just have one question. Is this still a problem ?! You probably will lose some mental and physiological defense systems. Science says this is actually a good thing to do occasionally. Scott Kelley, a 10-year Army veteran, knows about sleep deprivation. This may give you a clue as to the reason for your insomnia: * New supplements, medications, foods, beverages? Exercise will also help you sleep better at night. I don't know what to do. I'm not really anxious or stressed. Does your doctor have you on any type of steroid medication? At this point the muscle fatigue is really bad to the point that even sitting up is just... heavy. I haven't slept in about 48 hours. Also you will be hungry. sleep effects the chemistry of the body so a dramatic shift in sleep pattern will produce the effect you describe. Lots of coffee, loud music, brisk walks, and utter desperation. Donât binge eat after. With multiple deployments under his belt, Kelley has had many instances of ⦠And those changes should help you survive the day. After the first night, I couldnât sleep. I once stayed up for four days in grad school to finish some projects. No big deal. I have been taking Melatonin or Lorazepam and neither seems to work for me. For the first 17-18 hours, you don't really feel much except a little routine tiredness. Some people said I looked like death others just did a double take stare like they saw a zombie. Lasted about 3-4 weeks. TLDR: Not a whole heck of a lot that you can tell. X Research source With a little bit of preparation and a regular schedule, you'll be able to stay awake and push through to the end. I remember one time I had to take steroids for a week. My body is ready for bed, but my brain is not. Been there myself many times... As for the 'dire consequences' of a lack of sleep, as a medical layman I say to you: don't worry about it excessively. I'm miserable. It feels normal, then gets bad, then normal again like nothing happened and in the end it's heavenly, let me walk you through it. I slept but only about 15-20 minutes a day of real sleep. I've tried laying down and going to sleep, but its like trying to go to bed when you're totally wide awake. I've layed in bed for hours. I havent slept in 4-5 days, and by that I don't mean poor sleep, I mean I have NOT slept at all for 4 days. I feel your pain..! Although you should avoid going longer than 3-4 days without sleep, you can safely stay up for a few days as long as you plan to get full nights of sleep for 1-2 days afterwards. Seriously, though, welcome to the world of quite a few professions during their university years. If you have been able to sleep well before, the first thing to do is to figure out what may recently have changed. I tried switching on the TV, hoping I'd get sleepy and just doze off. 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