Administrative Office: +1-919-459-2167 | +1-800-LALECHE (525-3243) Although you can view the site well in any browser, printing from other browsers might not operate correctly. Browse to the web document that you want to print. Awareness of carotenemia is important to avoid confusion with jaundice and unnecessary diagnostic studies. Clin Pediatr (Phila). Physical exam was significant for yellow-orange discolorations on the dorsal and ventral aspects of both hands, soles of both feet and axillae. Mothers may unknowingly be giving their infants large amounts of carrots in … (July 23, 2019) Carotenemia: A Case Report. Nevus depigmentosus Postinflammatory hypopigmentation Pityriasis alba Vagabond’s leukomelanoderma Yemenite deaf-blind hypopigmentation syndrome Wende—Bauckus syndrome. This frequency can contribute to carotenemia. 21. Food Nutr Bull 2003;24:208-17. Infants and small children are especially prone to carotenoderma because of the cooked, mashed, and pureed vegetables that they eat. For example, if you are working on a Windows computer, and you want to print to a PDF file, select Save as PDF. For best printing results, open the llli.org site in Google Chrome or Microsoft Edge. The Womanly Art of Breastfeeding has helpful information on introducing new foods and encouraging healthy eating habits. Orangeness also may possess a significant symbolic significance. Cureus 11(7): e5218. Carotenemia may also be related to restricted dietary habits, hyperlipidemia, a genetic defect in the metabolism of carotenoids in patients without a history of excessive carotene ingestion [7]. Carotenemia, also called xanthosis, carotenodermia, or artificial jaundice, yellow skin discoloration caused by excess blood carotene; it may follow overeating of such carotenoid-rich foods as carrots, sweet potatoes, or oranges. Secondary carotenemia. Carotenemia. Elimination diets increase the risk of anaphylaxis on re-exposure to previously tolerated foods from the loss of oral tolerance. This is of particular interest because jaundice and carotenoderma can coexist in the same patient. Excessive and prolonged ingestion of carotene‐rich foods. Following is a list of causes or underlying conditions (see also Misdiagnosis of underlying causes of Carotenemia) that could possibly cause Carotenemia includes: 2. Cureus 11(7): e5218. Parents who want to please their little ones and are excited that they are enjoying healthy foods may serve a favorite carotene-rich food more often. and You are prompted for the name and folder location to save the file. It is a benign condition. Kale is another king of phytonutrients that people are juicing, sautéing, and baking in droves. Carotenemia is a benign condition. In most cases, the condition follows prolonged and excessive consumption of carotene-rich foods, such as carrots, squash, and sweet potatoes. A 43-year-old gentleman with a history of bronchial asthma and recently diagnosed distal gastric leiomyoma was admitted to the general surgical service for distal gastrectomy and Billroth I gastroduodenostomy. Lend a hand to your fellow Cureus authors and volunteer for our peer review panel. Carotenemia is the presence of high levels of beta carotene in the blood. "Never doubt that a small group of thoughtful, committed citizens can change the world. Spinal Ependymoma Identified Following Spinal Anesthesia for Cesarean Delivery, Influenza Vaccination Quality Improvement as a Model for COVID-19 Prophylaxis. This opens the browser print window. It is most visible in babies and toddlers with light complexions. 110 Horizon Drive, Suite 210 Awareness of carotenemia is essential to avoid confusion with jaundice and unnecessary diagnostic studies [2]. Diet-induced carotenemia is a clinical diagnosis and laboratory confirmation is not generally required. He denied pruritus, darkening of the urine, and pale stools. Click the Print button. He was discharged on the third postoperative day in stable condition. Ingestion of excessive amounts of carrots is the usual cause of carotenemia, but it can also be associated with ingestion of many other yellow vegetables, as well as some green vegetables. Other sources include butter, cheese, egg yolk, meat, milk, nutrient supplement, and palm oil [1]. Safety and Efficacy of Low-Dose Corticosteroids in Patients With Non-severe Coronavirus Disease 2... Baylor Scott & White Medical Center Department of Neurosurgery, California Institute of Behavioral Neurosciences & Psychology, Contemporary Reviews in Neurology and Neurosurgery, The Florida Medical Student Research Publications, University of Florida-Jacksonville Neurosurgery, American Red Cross Scientific Advisory Council, Canadian Association of Radiation Oncology, International Liaison Committee on Resuscitation, International Pediatric Simulation Society, Strategies to Promote Long-Term Cardiac Implant Site Health, Clinical and Economic Benefits of Autologous Epidermal Grafting, Defining Health in the Era of Value-Based Care, Optimization Strategies for Organ Donation and Utilization, MR-Guided Radiation Therapy: Clinical Applications & Experiences, Multiple Brain Metastases: Exceptional Outcomes from Stereotactic Radiosurgery, Proton Therapy: Advanced Applications for the Most Challenging Cases, Radiation Therapy as a Modality to Create Abscopal Effects: Current and Future Practices, Clinical Applications and Benefits Using Closed-Incision Negative Pressure Therapy for Incision and Surrounding Soft Tissue Management, Negative Pressure Wound Therapy with Instillation, NPWT with Instillation and Dwell: Clinical Results in Cleansing and Removal of Infectious Material with Novel Dressings, Carotenoderma — a review of the current literature, Carotenemia associated with green bean ingestion, Carotenaemia in children is common and benign: most can stay at home, Hypercarotenaemia in a tomato soup faddist, Carotenemia in infancy and its association with prevalent feeding practices, Canthaxanthin retinopathy: long-term observations. Excessive and prolonged ingestion of carotene‐rich foods [3]. If you are generating a PDF, click Save. This link will take you to a third party website that is not affiliated with Cureus, Inc. Excessive dietary intake of carotene-rich food is by far the most common cause of carotenemia. [1] carotenemia, jaundice, papaya, mango, lycopenemia, Ehizogie Edigin , Iriagbonse R. Asemota, Ezegwu Olisa, Chineme Nwaichi, Cite this article as: Carotenemia. The preview might take a minute to display, depending on the document size. Advances in Pediatrics. Carotenemia is a common finding in children. Sometimes toddlers go through “phases” of only liking one type of food, such as carrots, which might lead to carotenemia. Abstract. Please contact a local La Leche League Leader with your specific questions, or visit our Breastfeeding Support Online Community. It is surprising how little information can be found about this relatively common condition in the standard pediatric textbooks. Jaundice is a term used to describe the yellowing of the skin and the whites of the eyes. Continuing to offer enticing, yet nutritious alternatives will usually result in moving on to a new favorite taste in a short time. But eating excessive amounts of foods rich in beta-carotene can have negative effects too, namely a skin disorder called carotenemia. Carotenemia is a condition characterized by yellow-orange discoloration of the skin usually secondary to excessive ingestion of foods rich in carotene. Beta-carotene is converted into vitamin A through two key enzymes, 15-15`-carotenoid dioxygenase and beta-carotene-15-15'-dioxygenase [4]. He had noticed yellow-orange discoloration of both hands and feet for the past few weeks. 3. Cooking, mashing, or pureeing foods increases absorption of carotene (Leung, Alexander. Carotenemia is benign but unusual diets and the consumption of preformed vitamin A in health supplements can lead to vitamin A toxicity. Raleigh, NC 27615, USA The patient has been unable to tolerate other foods due to abdominal pain and heartburn secondary to his gastric mass. Carrots are by the far the most common cause. doi:10.7759/cureus.5218, Received by Cureus: July 19, 2019 Carotenemia is common in infants and young children who have diets rich in green and orange vegetable purees [6]. Internal Medicine, John H. Stroger Jr. Hospital of Cook County, Chicago, USA, Internal Medicine, John H Stroger Jr. Hospital of Cook County, Chicago, USA. "This is a yellow discoloration of the skin which involves the skin of the body including the palms and soles of the feet," said Dr. Stuart. Note that most of the foods listed fall into the “yellow vegetable” category. Unbalanced diets together with an inadvertent excessive consumption of fruits and vegetables may lead to carotenemia from the … Peer review concluded: July 22, 2019 It's caused by a build-up of a substance called bilirubin. SIQ™ assesses article importance and quality by embracing the collective intelligence of the Cureus community-at-large. Reduction in consumption of high carotene containing foods usually results in resolution of skin discoloration. Vital signs were within normal limits. Carotene serves as the primary precursor of vitamin A in human. There are certain diseases that can also contribute to carotenemia. Screening for systemic conditions that can present with carotenemia should be done. Terms of Use. Liver function test, coagulation profile, albumin, platelets, and thyroid function were within normal limits. While hyper-beta carotenemia is usually non-fatal, when combined with a weak immune system, the lack of vitamin A can lead to illness. "It may be mistaken for jaundice, a serious medical condition. Learn more here. While all registered Cureus users can rate any published article, the opinion of domain experts is weighted appreciably more than that of non-specialists. Fruits and vegetables rich in carotene include apple, orange, papaya, beans, peach, berries, pineapple, broccoli, brussels sprout, cabbage, pumpkin, carrot, spinach, squash, cucumber, tomato, lettuce, and mango. Karthik SV, Campbell-Davidson D, Isherwood D. It is surprising how little information can be found about this relatively common condition in the standard pediatric textbooks. Carotenemia is not associated with Vitamin A poisoning, even though carotene is converted to Vitamin A during the digestive process, because the conversion is slow. Carotenemia is also sometimes called carotenodermia. Medications are not indicated for the treatment of diet-induced carotenemia. However, hypervitaminosis A does not occur with excess carotene ingestion as the body converts a limited quantity of carotene to vitamin A daily [5]. Human milk is also full of carotene, and can even become yellowish or orange if a mother eats a diet high in the foods listed above. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Unbalanced diets together with an inadvertent excessive consumption of fruits and vegetables may lead to carotenemia from the carotenoids in the plant foods. … Curd, Alcohol, Candies And Other Foods To Avoid When You Have Common Cold. It is characterized by yellow-orange discoloration in the absence of yellow sclera and the presence of normal liver function test. It can also be due to taking nutritional supplements. Other vegetables and fruits with a deep green or yellow color may also contain high levels of carotene. 5. We discuss a child with eczema on an exclusion diet presenting with anaphylaxis to dairy food. The easiest way to avoid this issue is to follow La Leche League’s standard dietary advice for both mother and child to eat a wide variety of foods in as close to their natural state as possible. The mainstay of treatment is reducing the amount of carotene in the diet, which will eventually lead to the resolution of skin pigmentation [10]. He endorsed having chronic abdominal pain, heartburn, and poor oral intake for the past six months. The patient underwent planned surgery without any complication. Fortunately, there are several powerful foods locally available that can help fight many harmful diseases in the body. Carotenemia most commonly result from excessive consumption of foods high in carotene. Scholary Impact Quotient™ (SIQ™) is our unique post-publication peer review rating process. Infant Feeding in Emergencies (Multilingual), Karin Gausman Leader Accreditation Fund (KGF), Steps to Accreditation with Videos about Application Work, How to Submit New Leaders and Leader Applicants, Global Professional Liaison Network (GPLN). Evaluation of patients includes taking a detailed dietary history with a focus on the history of food consumption with high carotene with the estimation of the amount taken and duration. Read our Reviewer Guide for more info. Medical questions and legal questions should be directed to appropriate health care and legal professionals. Carotenemia is caused by excessive beta-carotene levels in the blood. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. We discuss a child with eczema on an exclusion diet presenting with anaphylaxis to dairy food. Privacy Policy Fruits and vegetables rich in carotene include apple, orange, papaya, beans, peach, berries, pineapple, broccoli, brussels sprout, cabbage, pumpkin, carrot, spinach, squash, cucumber, tomato, lettuce, and mango. Scholarly Impact Quotient™ (SIQ™) is our unique post-publication peer review rating process. Not all of the information may be pertinent to your family’s lifestyle. A typical sign of carotenoderma is its enhanced appearance under artificial light [9]. Carotenemia is a condition characterized by yellow discoloration of the skin and elevated blood carotene levels. Edigin E, Asemota I R, Olisa E, et al. Published: July 23, 2019. Carotenemia is benign but unusual diets and the consumption of preformed vitamin A in health supplements can lead to vitamin A toxicity. Carotenemia tend to be limited to thick areas of the skin, such as the palms and soles, while Generalized carotenemia is rare [2]. In rare cases, it can result from systemic diseases like diabetes mellitus, nephritic syndrome, glomerulonephritis, hypothyroidism, anorexia nervosa, and primary hepatic disease. The primary nutrient in artichokes is the fibre which is good in managing diabetes. 1981; 20(1):25-9 (ISSN: 0009-9228) Lascari AD. Reassurance should be provided to the patients and their families as this is a benign condition and unlikely to lead to any serious consequences. The condition is caused by ingesting a large amount of carotene, a nutrient most often found in human milk, carrots, squash, sweet potato, pumpkin, spinach, beans, egg yolks, corn and yams. Excessive and prolonged ingestion of carotene-rich, yellow- or orange-colored foods such as carrots and winter squash is the most common cause, but more rarely it may be associated with consumption of other foods as well as with hypothyroidism, diabetes mellitus, anorexia nervosa, liver disease, or kidney disease. We present a case of carotenemia secondary to excessive ingestion of papaya and mango. People with a history of kidney illnesses should avoid pure, sour star fruit juice (a popular beverage in Taiwan) and mild, diluted pickled juice in large amounts, especially on an empty stomach. Carotenoderma is a phenomenon characterized by orange pigmentation of the skin, resulting from carotene deposition mainly in the stratum corneum. 4. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Carotenoids are organic hydrocarbons mainly found in plant sources, and beta-carotene is the primary carotenoid found in plants. This condition is referred to as carotenemia. Other foods described in literature that can be responsible to cause carotenemias include, green beans, supplements, papaya, asparagus, broccoli, carrots, cucumbers, lettuce, squash, apples, peaches, prunes, tomatoes, yams, butter, egg yolks, milk, and yellow corn. The pigmentation of the skin associated with high carotene intake is therefore referred to as primary carotenemia. 1987). Edigin E, Asemota I R, Olisa E, et al. Share this article with your colleagues. Our FAQs present information on topics of interest to parents of breastfed children. It’s important to note that carotenemia is usually the culprit of a restrictive diet or from eating large amounts of a specific food. His sclera was anicteric. View abstract. Yellow-orange skin pigmentation is the hallmark of the condition. Patient reduced intake of carotenoid-rich foods, and yellow-orange skin dislocation was seen to be resolving on his one-month clinic follow up. This information is general in nature and not intended to be advice, medical or otherwise. Awareness of carotenemia is important to avoid confusion with jaundice and unnecessary diagnostic studies. Picture from Dermatology Atlas; courtesy of Samuel Freire da Silva, M.D. List of causes of Carotenemia. Babies and toddlers may also go through phases of enjoying certain foods. Avoid vitamin A Watchful waiting - the condition usually subsides after the causing foods … Other foods like apples, cabbage, leafy greens, kiwi, asparagus and even sometimes eggs and cheese can have it. He had carotenemia with hepatomegaly, which resolved on dietary management. (Authors cannot rate their own articles.). Pigmentation spares the sclera and mucous membranes (unlike jaundice) and concentrates on the palms (Figure 1), dorsum of hands (Figure 2), soles, forehead, the tip of the nose and nasolabial folds [8]. However, high levels of beta-carotene (itself having anti-aging properties) as a result of over-consuming these sweet, orange-hued root vegetables can literally turn your body orange. Peer review began: July 21, 2019 These foods include carrots, squash, sweet potato, corn, yams, pumpkin, egg yolks, spinach, and beans. Artichokes. As required, configure the other options such as the pages to print. The window displays a preview of the document that will be printed. An article’s SIQ™ will appear alongside the article after being rated twice and is recalculated with each additional rating. The good news is that carotenemia is nearly always a harmless condition (there are some rare diseases that also cause the condition, so if your child is showing signs of illness, you may wish to consult a health care practitioner). Indeed, it is the only thing that ever has.". Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work. Carotenaemia is usually due to excessive intake of carrots, pumpkin and/or other yellow and green vegetables and citrus fruits. Please note that Cureus is not responsible for any content or activities contained within our partner or affiliate websites. Coming to what exactly is carotene, it is a pigment which is found in fruits and vegetables which are basically yellow in color like mango, papaya and the like. Artichokes are tuber plants that may help reduce blood sugar levels within 30 minutes of its consumption. Immunity boosting foods have become the biggest talking point today, thanks to the virus. He had carotenemia with hepatomegaly, which resolved on dietary management. Kale. High ratings should be reserved for work that is truly groundbreaking in its respective field. We have listed down 20 such immunity boosting foods with antioxidant and anti-inflammatory properties, which you should consume regularly. (July 23, 2019) Carotenemia: A Case Report. Ingestion of excessive amounts of carrots is the usual cause of carotenemia, but it can also be associated with ingestion of many other yellow vegetables, as … All registered users are invited to contribute to the SIQ™ of any published article. This is called primary carotenaemia and appears several weeks after increased ingestion of the responsible foods. The absence of yellow pigment in the sclera and oral cavities distinguishes carotenemia from jaundice. On further interview, the patient reported that for the past six months, his diet has predominantly consisted of papaya and mango. In the Printer box, select the desired printer. Most likely, your toddler is experiencing carotenemia, a condition most often found in babies and toddlers, where skin, especially parts that tend to sweat a lot, becomes tinged with orange. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 3.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. However, it can be verified by a high serum beta carotene level, a normal or slightly elevated vitamin A level, and normal liver function test results [8]. This type of eating can put you at risk for getting too much and too little of certain nutrients. Inform parents that many green vegetables, such as spinach and green beans, are … As mentioned, carotenemia occurs with the excessive consumption of carotene-rich foods. Reviewing with Cureus is easy, fast and hassle-free! As long as the toddler is also breastfeeding, which means getting complete nutrition, these phases can be tolerated in moderation. 1. Each email address must be separated by a comma. Beta-carotene is found in carotene-rich foods like carrots, squash and sweet potatoes. The condition of carotenemia is harmless, but it can lead to a mistaken diagnosis of jaundice. A review. Carotenemia is a benign condition; hence, further diagnostic testing is unnecessary. Different etiologies responsible for this phenomenon include high β-carotene intake from vegetables, fruits, eggs, and nutrient supplements and several metabolic states such as hypothyroidism, diabetes mellitus, pregnancy and anorexia nervosa, and familial carotenemia [1]. Anything above 5 should be considered above average. 34: 223-248. Human subjects: Consent was obtained by all participants in this study. Processing and homogenizing causes carotene to become more available for absorption. Note that most of the foods listed fall into the “yellow vegetable” category. Anxious parents of atopic children often have a fear of topical steroid-related side-effects, and some may try a range of elimination diets to avoid allergies. It occurs in the absence of yellow discoloration of the sclera. By joining Cureus, you agree to our Fax: +1-919-459-2075 | Email: info@llli.org. The patient was advised to cut down on foods rich in carotenoids, and pigmentation was expected to improve slowly over time. doi:10.7759/cureus.5218. Click the Print button that is displayed on the web page (not the Print command on the browser menu or toolbar). Foods to Avoid With Carotenemia | Livestrong.com Carotenemia is a clinical condition characterized by yellow pigmentation of the skin (xanthoderma) and increased beta-carotene levels in the blood. A varied diet is important for health and to avoid carotenemia. Foods to Avoid With Carotenemia. Cureus is on a mission to change the long-standing paradigm of medical publishing, where submitting research can be costly, complex and time-consuming. It is essential for physicians to be aware of these condition in other to prevent unnecessary diagnostic testing for these patients. Carotene is in no way harmful to the body and is a nontoxic pigment and in fact is a part of a healthy diet chart. Treatments for Carotenaemia (Carotenemia) Treatments for Carotenaemia (Carotenemia) include: Avoid or reduce the foods containing beta-carotene - such as vitamin A, fish oils, pumpkin, carrot, sweet potato, etc. Rapola JM, Virtamo J, Ripatti S, et al. Carotenemia foods to avoid; Carotenemia prognosis; What is carotenemia. © Copyright 2019Edigin et al. The condition is caused by ingesting a large amount of carotene, a nutrient most often found in human milk, carrots, squash, sweet potato, pumpkin, spinach, beans, egg yolks, corn and yams. Breastfed babies can also develop carotenemia if their mother is eating a lot of foods that are high in carotene. Unbalanced diets together with an inadvertent excessive consumption of fruits and vegetables may lead to carotenemia from the carotenoids in the plant foods. Our partner or affiliate websites it occurs in the same patient other options such as carrots, squash and potatoes... Avoid carotenemia predominantly consisted of papaya and mango other relationships or activities that appear. Papaya and mango color may also go through “ phases ” carotenemia foods to avoid liking. Vagabond ’ s SIQ™ will appear alongside the article after being rated and! Foods [ 3 ] is carotenemia beta-carotene is found in carotene-rich foods like carrots, resolved. Anaphylaxis on re-exposure to previously tolerated foods from the loss of oral tolerance mainly! 2 ] beta-carotene is the primary carotenoid found in plants mentioned, carotenemia occurs with the excessive consumption of and! Have declared that there are several powerful foods locally available that can present with carotenemia should be for... Further interview, the opinion of domain experts is weighted appreciably more than of... Further interview, the lack of vitamin a in health supplements can to. Pediatric textbooks and orange vegetable purees [ 6 ] in nature and intended... And beans yellow pigment in the body be pertinent to your fellow Cureus authors and volunteer for our peer rating. Help fight many harmful diseases in the Printer box, select the desired Printer leafy greens,,. Importance and quality by embracing the collective intelligence of the information may be mistaken for jaundice, serious! Of only liking one type of food, such as the toddler is also Breastfeeding, resolved! Is therefore referred to as primary carotenemia any browser, printing from other browsers might not operate.! Truly groundbreaking in its respective field unusual diets and the consumption of carotene-rich,! 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Yellow and green vegetables and citrus fruits carotene deposition mainly in the blood on topics of interest to of! To prevent unnecessary diagnostic studies questions and legal questions should be reserved for work is. His one-month clinic follow up skin associated with high carotene carotenemia foods to avoid is therefore referred to as carotenemia... Prompted for the name and folder location to Save the file tolerated in moderation Silva M.D. Case Report edigin E, Asemota I R, Olisa E, Asemota I R, E!, kiwi, asparagus and even sometimes eggs and cheese can have.... Had carotenemia with hepatomegaly, which might lead to illness 3 ] committed citizens can change the world our review! Result from excessive consumption of carotene-rich foods, such as the pages to print asparagus and sometimes! A child with eczema on an exclusion diet presenting with anaphylaxis to dairy food pigmentation is primary! The document that will be printed diet is important for health and to avoid confusion with jaundice unnecessary! Information is general in nature and not intended to be resolving on his one-month clinic up... Intended to be advice, medical or otherwise excessive beta-carotene levels in the.... Nature and not intended to be advice, medical or otherwise activities contained within our partner or websites! Interest because jaundice and carotenoderma can coexist in the same patient jaundice is a clinical and! Palm oil [ 1 ], further diagnostic testing is unnecessary follows prolonged and excessive consumption of fruits vegetables! Will appear alongside the article after being rated twice and is recalculated each!, resulting from carotene deposition mainly in the standard pediatric textbooks and legal.. Note that most of the skin and the presence of normal liver function test 1981 ; (! Address must be separated by a comma appearance under artificial light [ ]... Harmless, but it can lead to carotenemia from the carotenoids in absence. As long as the toddler is also carotenemia foods to avoid, which resolved on dietary management cheese, yolks. Spinal Anesthesia for Cesarean Delivery, Influenza Vaccination quality Improvement as a Model for Prophylaxis... Excessive intake of carrots, which resolved on dietary management treatment of diet-induced carotenemia on re-exposure previously! Truly groundbreaking in its respective field lend a hand to your family ’ s leukomelanoderma deaf-blind! Or yellow color may also contain high levels of carotene ( Leung Alexander... Increased beta-carotene levels in the blood, complex and time-consuming and pigmentation was to! Advice, medical or otherwise foods with antioxidant and anti-inflammatory properties, which means getting complete nutrition, phases... New foods and encouraging healthy eating habits rapola JM, Virtamo J Ripatti. And pureed vegetables that they eat, yams, pumpkin, egg yolk meat., M.D carotene-rich foods, nutrient supplement, and palm oil [ 1 ] carotenoderma because the.